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Management for fistula‐in‐ano with Ginseng and Tang‐kuei Ten Combination
Author(s) -
Ohya Toshiki,
Usui Yoshiko,
Okamoto Kentaro,
Inoue Yumi,
Arii Shigeki,
Iwai Takehisa
Publication year - 2004
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.2004..x
Subject(s) - medicine , curettage , abscess , surgery , fistula , peri , perianal abscess
Background: Non‐operative management for patients with fistula‐in‐ano in infancy using a traditional herbal medicine Ginseng and Tang‐kuei Ten Combination (GTTC) is described.Methods: A total of 22 patients with peri‐anal abscess or fistula‐in‐ano were treated with GTTC. Eighteen patients showed no improvement using the conventional non‐operative management (frequent curettage of abscess cavity), after which administration of GTTC was commenced. The other four patients received GTTC from the beginning of their treatment. A dose of 0.1−0.2 g/kg of GTTC was given orally twice a day. The period between onset of peri‐anal abscess and the commencement of GTTC (pre‐GTTC period) was compared to the period until remission after administration of GTTC (post‐GTTC period). The relationship between the GTTC dose, age at onset of peri‐anal abscess, post‐GTTC period, and relapse rates were investigated.Results: Twenty‐one patients reached remission, but a 4‐year‐old boy failed to reach remission and he required fistelectomy. Pre‐GTTC periods were from 11 days to 3 years (median 50 days) and statistically longer than post‐GTTC periods (4−65 days, median 7 days). There was a reverse correlation between the age at onset of peri‐anal abscess and post‐GTTC period ( r = −044, P < 0.05). There was no statistical correlation between the dose of GTTC and post‐GTTC period. Five patients showed relapse after discontinuing GTTC, all of them could be resolved with augmentation of the dose. The onset of peri‐anal abscess in patients who relapsed were all < 3 months of age.Conclusion: Ginseng and Tang‐kuei Ten Combination seemed to accelerate the recovery of patients with fistula‐in‐ano in infancy.