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A case of Epstein‐Barr virus infection with exophthalmos and ocular muscle swelling
Author(s) -
SUGIYAMA KENJI,
ITO MASAHIRO,
ICHIMI RYOJI,
HIGASHIKAWA MASAMUNE,
KAWASAKI HAJIME,
KOMADA YOSHIHIRO,
SAKURAI MINORU,
WAKIGUCHI HIROSHI,
KIKUTA HIDEAKI,
FUKAYAMA MASAHISA
Publication year - 1997
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1997.tb03670.x
Subject(s) - medicine , exophthalmos , epstein–barr virus , lymph , cyclophosphamide , pathology , virus , immunology , chemotherapy , surgery
A 14‐year‐old girl with Epstein‐Barr virus (EBV) infection developed exophthalmos and ocular muscle swelling. The EBV genome was detected in T lymphocytes taken from the submandibular gland, temporal muscle and cervical lymph nodes. A surface marker analysis of her peripheral blood demonstrated that CD45RO‐positive T lymphocytes were strongly activated. Immunosuppressive treatment, including steroid and cyclophosphamide, was effective in improving the symptoms. Immunosuppressive therapy may be included as the choice of treatment for EBV infection.