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Heart disease in Friedreich's ataxia: A clinical and echocardiographic study
Author(s) -
GÜNAL NAZLIHAN,
SARAÇLAR MUHSIN,
ÖZKUTLU SÜHEYLA,
ŞENOCAK FILIZ,
TOPALOǦLU HALUK,
KARAASLAN SEVIM
Publication year - 1996
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1996.tb03496.x
Subject(s) - medicine , ataxia , cardiology , dilated cardiomyopathy , left ventricular hypertrophy , cardiomyopathy , incidence (geometry) , heart disease , muscle hypertrophy , heart failure , blood pressure , physics , psychiatry , optics
Twelve patients with Friedreich's ataxia (FA) were evaluated clinically and echocardiographically for evidence of heart disease. Electrocardiographic and echocardiographic abnormal findings were discovered in eight (67%) and seven (58%) children, respectively. A high incidence of cardiac involvement is well known in FA cases. Although the patient number in the present study is small, the findings are consistent with those in the literature. The most common pathology was asymmetric septal hypertrophy (ASH), followed by concentric left ventricular hypertrophy (CLVH) and dilated cardiomyopathy (DC).