Premium
Immunogenicity of the whole antigen and glycoprotein I of varicella‐zoster virus (VZV) and the VZV skin test antigen
Author(s) -
KAWANO SHOJI,
TERADA KIHEI,
HIRAGA YUMIKO,
MORITA TETSURO
Publication year - 1996
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1996.tb03452.x
Subject(s) - immunogenicity , antigen , varicella zoster virus , medicine , virology , immunology , virus , immune system
Specific cellular immunity against the whole antigen and glycoprotein I (gp I) of varicella‐zoster virus (VZV) and the skin test antigen were determined for 13 healthy immune adults to compare the immunogenicity of these antigens using a lymphoproliferative assay. The stimulation index values (mean ± s.d.) were 16.4 ± 11.2 against the whole VZV antigen, 4.2 ± 2.9 against the VZV skin test antigen and 1.1 ±0.5 against gp I. The immunogenicity of the skin test antigen, which mainly contains gp III and gp IV, appears to be more favorable than that of gp I alone, but to be weaker than that of the whole VZV antigen.