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Long‐term sequential changes of antibody to p40 tax in HTLV‐I carrier mothers and children
Author(s) -
KUSUHARA KOICHI,
UEDA KOHJI,
TOKUGAWA KEN,
MIYAZAKI CHIAKI,
OKADA KENJI,
SAWADA TAKASHI
Publication year - 1995
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1995.tb03397.x
Subject(s) - medicine , antibody , population , pediatrics , demography , immunology , environmental health , sociology
Antibody to p40 tax (anti‐p40 tax ) in serum specimens obtained sequentially from a human T cell lymphotropic virus type I carrier population of mothers and children were assayed. The prevalences of anti‐p40 tax at the initial sampling were 88% (7/8) in children and 55% (16/29) in mothers. Two of the seven positive children lost their anti‐p40 tax during the investigation period, resulting in a final prevalence of 63% (5/8) in children. However, anti‐p40 tax status was constant in all the 22 mothers with multiple serum samples (15 remained positive and seven remained negative). A decline in the absorbance value of EIA for anti‐p40 tax was observed in seven of the 15 anti‐p40 tax positive mothers. This decline may result in the disappearance of anti‐p40 tax in some of them.