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Acute renal failure after exercise in a child with renal hypouricemia
Author(s) -
FUJIEDA MIKIYA,
YOKOYAMA WAKAKO,
OISHI NAOBUMI,
OKADA TAISUKE,
KURASHIGE TAKANOBU,
HAMADA GIBUN
Publication year - 1995
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1995.tb03394.x
Subject(s) - medicine , uric acid , hypouricemia , probenecid , creatinine , blood urea nitrogen , renal physiology , pyrazinamide , excretion , reabsorption , renal function , gastroenterology , uricosuric , endocrinology , urology , kidney , hyperuricemia , pathology , tuberculosis , isoniazid
We describe a 15 year old boy with renal hypouricemia who developed acute renal failure after a school athletics meeting, accompanied by appendicitis. During acute renal failure, the highest level of uric acid was 5.0 mg/dL, creatinine 7.9 mg/dL and urea nitrogen 58.6 mg/dL. After recovery, the serum uric acid fell to 0.9 mg/dL and the fractional excretion of uric acid (FEu A ) exceeded the normal range. The probenecid and pyrazinamide tests showed that the patient had a total defect of uric acid reabsorption. This case suggested that strenuous exercise could be responsible for acute renal failure in patients with renal hypouricemia.