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Successful autologous bone marrow transplant for relapsed Ki‐1 lymphoma
Author(s) -
TAKAMURA MAYUMI,
MUGISHIMA HIDEO,
NAGATA TOSHIHITO,
SHICHINO HIROYUKI,
SHIMADA TOSHIAKI,
SUZUKI TAKASHI,
CHIN MOTOAKI,
HARADA KENSUKE,
FUJIMOTO ZYUNICHIRO
Publication year - 1995
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1995.tb03373.x
Subject(s) - medicine , lymphoma , bleomycin , vincristine , bone marrow , chemotherapy , lymph node , cyclophosphamide , transplantation , surgery , oncology
We report on a 16 year old girl with relapsed Ki‐1 lymphoma and a very poor prognosis. The initial manifestation was multiple bone metastases and lymphadenopathy. The patient achieved remission with modified adriamycin, bleomycin, vincristine, daunomycine therapy. However, 14 months after the completion of therapy, relapse occurred in a new cervical lymph node on the left side. After preparation with chemotherapy and total lymphoid irradiation (TLI) the patient underwent autologous bone marrow transplantation (A‐BMT). Ki‐1 lymphoma shows clinically diverse symptoms, but hematopoietic stem cell transplantation should be performed in relapsed cases. It may be effective to give TLI followed by A‐BMT for patients such as ours who have lymph node involvement without bone marrow metastasis.