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Hemolytic anemia following high‐dose intravenous immunoglobulin administration
Author(s) -
TAMADA KOHICHI,
KOHGA MASATOSHI,
MASUDA HIDEKO,
HATTORI KAZUMI
Publication year - 1995
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1995.tb03339.x
Subject(s) - medicine , hemolytic anemia , antibody , anemia , adverse effect , thrombocytopenic purpura , thrombotic thrombocytopenic purpura , autoimmune hemolytic anemia , immunoglobulin g , immunology , immune system , platelet
We describe two cases of hemolytic anemia following high‐dose intravenous human immunoglobulin administration in young females with idiopathic thrombocytopenic purpura. Inducement of hemolytic anemia by anti‐A and anti‐B antibodies in these cases necessitates the performance of a minor crossmatching procedure prior to immunoglobulin use to prevent the occurrence of this adverse reaction.