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Mononucleosis‐like illness in an infant associated with human herpesvirus 6 infection
Author(s) -
KANEGANE CHIHARU,
KATAYAMA KEITA,
KYOUTANI SEIZO,
KANEGANE HIROKAZU,
SHINTANI NAOHISA,
MIYAWAKI TOSHIO,
TANIGUCHI NOBORU
Publication year - 1995
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1995.tb03304.x
Subject(s) - mononucleosis , medicine , human herpesvirus 6 , lymphocytosis , virology , immunology , virus , antibody , herpesviridae , viral disease
Illnesses resembling mononucleosis, hematologically characterized by atypical lymphocytosis in the peripheral blood, are caused by other viral infections as well as by a primary Epstein‐Barr virus infection. Human herpesvirus 6, a newly isolated member of the herpesvirus group, can also cause a mononucleosis‐like illness. Illness associated with human herpesvirus 6 infection mostly occurs in immunocompetent adults. We observed a 3 month old infant who presented with marked atypical lymphocytosis and liver dysfunction. We examined serum samples to detect viral antibodies related to mononucleosis‐like illness. Only the titers of antibody against human herpesvirus 6 were elevated. Primary human herpesvirus 6 infection cannot only cause exanthem subitum or present in an inapparent form but can also cause an illness like mononucleosis, even in an infant.