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Increased levels of antibodies to food proteins in Down syndrome
Author(s) -
REICHELT KARL L,
LINDBACK TORE,
SCOTT HELGE
Publication year - 1994
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1994.tb03231.x
Subject(s) - medicine , antigen , antibody , immunology , immunoglobulin a , food protein , immunoglobulin g , biology , biochemistry
An increased level of immunoglobulin A (IgA) antibodies to food antigens has been found in Down syndrome. Biopsy did not show any anomaly of the gut. Increased IgA levels against specific proteins reflect increased transmucosal transport of antigens. The antigens presented may be immunogenic peptides or intact antigens. In this paper, we wished to exclude an institutional cause such as infections and also age differences.