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Haemophilus influenzae type D infection and JgG2 deficiency in a patient with chronic mucocutaneous candidiasis
Author(s) -
SAKANO TAKASHI,
HAMASAKI TAKASHI,
MORI MIKIO,
TAKAHASHI HIROKO
Publication year - 1994
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1994.tb03166.x
Subject(s) - medicine , chronic mucocutaneous candidiasis , mucocutaneous zone , dermatology , microbiology and biotechnology , haemophilus influenzae , antibiotics , disease , biology
A 14 year old boy with chronic mucocutaneous candidiasis and persistent pulmonary infection caused by Haemophylus influenzae and Streptococcus pneumoniae is reported. Initial bacterial culture studies showed H. influenzae type B and S. pneumoniae as causative agents. H. influenzae type D was constantly isolated from the patient's sputum. Abnormally low levels of serum immunoglobulin G2 (IgG2) found in the patient may have contributed to the pulmonary infection and H. influenzae type D may be an important causative agent in immunodeficient patients.