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Histopathologic evidence for cardiomyopathy in a child with mitral valve prolapse
Author(s) -
NAKADA TOSHIMASA,
YONESAKA SUSUMU
Publication year - 1993
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1993.tb03102.x
Subject(s) - medicine , mitral valve prolapse , cardiology , cardiomyopathy , endomyocardial biopsy , biopsy , restrictive cardiomyopathy , myocardial fibrosis , mitral valve , fibrosis , heart failure
An intriguing relationship between idiopathic mitral valve prolapse (MVP) and cardiomyopathy has been reported in adult cases of MVP. This paper reports a girl with idiopathic MVP, who presented with progressive cardiomegaly and cardiomyopathic findings on cardiac biopsy; right ventricular endomyocardial biopsy at the age of 15 years showed myocardial hypertrophy, disarray, myocardial degeneration, interstitial fibrosis and endocardial thickening. To our knowledge, this is the first case of idiopathic MVP in childhood that has been shown to have positive biopsy findings for cardiomyopathy.