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Varicella infection complicated with meningitis after immunization
Author(s) -
NARUSE HIROSHI,
MIWATA HIROYUKI,
OZAKI TAKAO,
ASANO YOSHIZO,
NAMAZUE JUNKO,
YAMANISHI KOICHI
Publication year - 1993
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1993.tb03067.x
Subject(s) - medicine , aseptic meningitis , meningitis , seroconversion , virology , immunization , varicella vaccine , viral meningitis , pleocytosis , lymphocytic pleocytosis , cerebrospinal fluid , polymerase chain reaction , complication , immunology , pediatrics , virus , antibody , encephalitis , pathology , bacterial meningitis , biochemistry , chemistry , gene
A healthy 45 month old boy who had received varicella vaccine 21 months previously developed aseptic meningitis along with an episode of varicella. The presence of viral DNA in cerebrospinal fluid (CSF) detected by polymerase chain reaction (PCR) with Southern blot hybridization confirmed the relationship between the symptoms and the CSF pleocytosis. This is the first reported case of this complication of varicella meningitis occurring in a child with documented immunization and seroconversion.