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Granulocyte elastase α 1 ‐proteinase inhibitor complex measurement in very low birthweight infants with severe intraventricular hemorrhage
Author(s) -
TAKASAKI JIRO,
KAMIYA KENJI,
OGAWA YUNOSUKE,
TANAKA TAIHEI,
KOYAMA NORIHISA
Publication year - 1993
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1993.tb03016.x
Subject(s) - medicine , intraventricular hemorrhage , proteinase inhibitor , elastase , granulocyte , low birth weight , neutrophil elastase , pediatrics , anesthesia , gestational age , biochemistry , enzyme , pregnancy , chemistry , genetics , inflammation , biology
We investigated the relationship between the levels of granulocyte elastase α 1 ‐proteinase inhibitor complex (E‐α 1 ‐PI) in plasma and severe intraventricular hemorrhage (IVH) in very low birthweight infants. The concentrations of E‐α 1 ‐PI and the ratio of the concentrations of E‐α 1 ‐PI to polymorphonuclear leucocyte counts within 24 h of birth in infants with severe IVH were significantly higher compared with those in infants without severe IVH. E‐α 1 ‐PI seems to be a useful indicator of IVH.