Premium
Standards for Growth and Growth Velocity in Turner's Syndrome
Author(s) -
Suwa Seizo
Publication year - 1992
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1992.tb00951.x
Subject(s) - medicine , turner syndrome , growth velocity
Turner‐specific natural growth and growth velocity curves based on the retrospectively surveyed growth data of 704 Japanese patients in a mixed cross‐sectional and longitudinal mode are reported. There was no significant difference in growth between the patients with karyotype 45,X and non‐45,X. Twenty‐three patients had a history of genital bleeding between the ages of 11 and 14 years (12 years ± 9 months). The mean height of the patients with genital bleeding did not differ significantly from that without bleeding from birth until 1 year 3 months of age but thereafter the former were always significantly taller than the latter. The former ceased growing after 18 years; on the other hand the latter were still growing after 18 years and then the final height of each group of patients became almost the same (139.6 ± 3.5 cm in the former and 139.1 ± 5.6 cm in the latter). A slight and gentle growth spurt was observed during the expected adolescent period in both groups, with and without genital bleeding. However, the mean height of peak (1.3 ± 0.95 cm/year) and the mean peak velocity (5.2 ± 1.1 cm/year) in the patients with genital bleeding were significantly higher than those (0.7 ± 0.36 and 3.8 ± 0.6 cm/year, respectively) in the patients without genital bleeding.