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Infant Botulism with Down Syndrome
Author(s) -
Toyoguchi Sho,
Tsugu Hitoshi,
Nariai Akiyoshi,
Kaburagi Yoichi,
Asahina Yoshiko,
Ambo Kazutoshi,
Katou Kazuo
Publication year - 1991
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1991.tb01573.x
Subject(s) - medicine , botulism , clostridium botulinum , feces , stridor , pediatrics , paralysis , flaccid paralysis , respiratory failure , toxin , anesthesia , surgery , microbiology and biotechnology , airway , biology
A 4‐month‐old boy with Down syndrome and infant botulism is reported. He was admitted to our hospital with stridor and developed respiratory failure and generalized paralysis. Laboratory examination revealed botulinal toxin type A in his blood and feces. Clostridium botulinum organisms were found in the feces and in the honey which he had been fed. Anti‐botulinal toxin was administered on the 10th day of illness. Artifical ventilation was given for 87 days and he survived. This is the 11th known case of infant botulism in Japan. It is possible that other cases remain undiagnosed.