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An Epidemic of Meningococcal Disease in Karachi (Pakistan): A Study of Children
Author(s) -
DureSamin Akram,
Mubina Agboatwalla,
Azra Yasmin
Publication year - 1991
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1991.tb01565.x
Subject(s) - medicine , meningococcal disease , penicillin , disease , pediatrics , prospective cohort study , meningococcal infections , population , neisseria meningitidis , intensive care medicine , antibiotics , environmental health , biology , bacteria , microbiology and biotechnology , genetics
A prospective study of 112 cases of epidemic meningococcal infection in the paediatric population is presented. The natural course of the disease, its complications, prognostic factors and therapeutic agents were studied. The cases were graded according to fixed criteria of severity which correlated well with the outcome of the disease. The gram‐stain of the CSF was a sensitive and a quick method of diagnosis and crystalline penicillin a cost‐effective therapy giving a good response within 48 hours in 90% of the cases.