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Treatment of Status Asthmaticus—Hormone Changes before and after Aminophylline i.v. Drip Therapy
Author(s) -
Likura Yoji,
Kishida Masaru,
Akasawa Akira,
Nagakura Toshikazu,
Akimoto Kenichi,
Saito Hirohisa,
Koya Niroku,
Sasamoto Akiyoshi
Publication year - 1990
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1990.tb00814.x
Subject(s) - medicine , asthma , aminophylline , hormone , antidiuretic , inhalation , anesthesia , intensive care medicine
The treatment of status asthmaticus is one of the most important factors in controlling the patient with asthma attacks. We have studied hormone changes in status asthmaticus and considered what is the best treatment in the asthma attack condition in children. Antidiuretic hormone (ADH), renin activity, and aldosterone activity are elevated in severe asthma attack conditions, and these high levels are correlated with high levels in Wood's clinical score. It is theoretical that patients with dehydration and respiratory failure show such elevation in hormones, and it is well known that under such conditions β 2 ‐stimulant enhances renin production. From our study, it is concluded that β 2 2 ‐stimulant subcutaneous injection must be considered in status asthmaticus. In children, amminophylline i.v. drip therapy may be one of the best treatments in status asthmaticus.