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Histiocytosis X: Successful Treatment with Recombinant Interferon‐αA
Author(s) -
Sato Yuichi,
Ikeda Yasuhiko,
Ito Etsuro,
Miyano Takakazu,
Kawauchi Kyoichi,
Yokoyama Masaru,
Kamata Yoshimasa
Publication year - 1990
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1990.tb00801.x
Subject(s) - medicine , histiocytosis x , interferon , histiocytosis , recombinant dna , dermatology , pathology , immunology , disease , biochemistry , chemistry , gene
Two patients with disseminated histiocytosis X were treated with intramuscular injections of recombinant interferon αLA. The bone, skin and visceral lesions of these patients diminished rapidly. Significant sclerosis and recalcification of bone were observed. From our limited but positive experience, it would be justified to consider the use of interferon in patients with disseminated histiocytosis X.