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Acromesomelic Dysplasia in a Father and Son: Autosomal Dominant Inheritance
Author(s) -
Ohba Kenichi,
Ohdo Shozo,
Sonoda Tohru,
Madokoro Harumichi
Publication year - 1989
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1989.tb01360.x
Subject(s) - medicine , inheritance (genetic algorithm) , genetics , autosomal recessive inheritance , gene , biology
A father and son with typical acromesomelic dysplasia are reported, with the father more severely affected than the son. The disease was thus apparently transmitted in an autosomal dominant fashion. This is at variance with the autosomal recessive mode of inheritance assumed from hitherto reported families.