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Phosphorus Deficiency Syndrome in Two Very Low Birthweight Infants
Author(s) -
Tsukahara Hirokazu,
Sakaguchi Tadahiko,
Mitsuyoshi Izuru,
Fukuhara Hitoo,
Hayashi Shuhei,
Nakamura Katsuji
Publication year - 1988
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1988.tb02546.x
Subject(s) - medicine , hypophosphatemia , rickets , phosphorus , alkaline phosphatase , osteopenia , phosphorus deficiency , endocrinology , pediatrics , elevated alkaline phosphatase , calcium , physiology , vitamin d and neurology , osteoporosis , biochemistry , bone mineral , chemistry , materials science , metallurgy , enzyme
Biochemical and radiographic abnormalities linked with phosphorus deficiency syndrome (PDS) developed in two very low birthweight (VLBW) infants fed exclusively with human milk. By increasing phosphorus (P) and calcium (Ca) intakes with the introduction of a specialized premature formula, osteopenia or rickets, as well as hypophosphatemia, hypo‐phosphaturia and increased serum alkaline phosphatase levels improved in both patients. We speculated that all VLBW infants who are being fed exclusively with human milk should be monitored for PDS and that if PDS develops, supplementation of human milk with both P and Ca appears to be necessary for its treatment.