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Continuous Nasogastric Infusion of Prostaglandin E2 in Ductus‐Dependent Congenital Heart Disease
Author(s) -
Komiyama Osamu,
Osano Mitsuru.,
Oikawa Tadao,
Morikawa Yoshiyuki,
Kojima Yoshifumi,
Murai Takayasu,
Ishihara Jun,
Tokumura Mitsuaki,
Taguchi Nobuhiko
Publication year - 1988
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1988.tb01579.x
Subject(s) - medicine , ductus arteriosus , pulmonary atresia , prostaglandin e2 , anesthesia , prostaglandin , regimen , heart disease , cardiology
Prostaglandin E2 (PGE2) was infused continuously through a nasogastric gavage tube in four infants with pulmonary atresia. The drug was given at a rate of 12.5–160 µg/kg/h. The duration of therapy was 7–123 days. The effects and side effects seen by this method were similar to those seen in the conventional multiple dose regimen. This method was an effective and simple way of maintaining the ductus arteriosus open, especially for a long period of time.