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Endocrine Changes of the Hypothalamic, Pituitary and Adrenal Systems in Cyclic Vomiting
Author(s) -
Aritaki Sekoiya,
Ogihara Masaaki,
Kusakawa Isao,
Takamiya Hikari,
Hori Yoshihiro,
Kawashima Naoshi,
Miyajima Tasuku,
Chiba Tomoyuki,
Tsuyuki Kazumitsu,
Takekuma Koji,
Matsuno Tetsuhiko,
Honda Teruo
Publication year - 1986
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1986.tb00742.x
Subject(s) - medicine , endocrinology , vomiting , prolactin , plasma renin activity , epinephrine , metanephrine , hormone , blood pressure , renin–angiotensin system
Children with cyclic vomiting had high blood ADH, ACTH, cortisol and plasma renin activity (PRA) during vomiting, and urinary excretion of 170HCS, 17KGS, 17KS, norepinephrine (NE), epinephrine (E), normetanephrine (NMN), metanephrine (MN) and vanillylmandelic acid (VMA) was increased. After disappearance of the vomiting, the levels fell to within the normal range. Variation was not observed in blood prolactin (PRL), Na, osmotic pressure or urine dopamine (DA). Normal findings were obtained in the intravenous water loading test, response of anterior pituitary hormones and cortisol to the insulin, TRH and LH‐RH loading, the metopirone test and the dexamethasone suppression test which were performed 1 week after the vomiting.