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Changing pattern in Reserve Capacity of Gonatropin Secretion
Author(s) -
Hoshina Kiyoshi,
Yoshida Yasuko,
Kambara Misuzu,
Tsukada Kazuko
Publication year - 1986
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1986.tb00720.x
Subject(s) - medicine , prepuberty , age groups , endocrinology , physiology , demography , hormone , sociology
Reserve capacity of Lh and FSH secretion was examined by standarized LHRH loading rest in 30 endocrinologically normal children, whose age ranged from 3 to 13 years. These sunjects were divided by sex. Both male and female subjects were divided into three groups by their chronological age, that is, Group A: under 6 years, Group B: 7 to 10 years and Group C: over 11 years of age. In the male the peakl values of LH were 10.86 ± 1.9 (mean ± SD) for Group a, 23,3 ± 7.3 for Group B, and 73.13 ± 6.4 mIU/ml for Group C. Corresponding values in the female were 8.58 ± 1.3, 20.56 ± 3, and 60.38 ± 8.5 mIU/ml, respectively. These intergroup differences in the peak LH values weer statistically significant (p<0.01)in both sexes. Regarding peak FSH values, no difference was seen among groups of either male or female cases. These findings indicate that even in prepuberty the reserve capacity of LH secretion begins to increase around the age of about 7 years.