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Increased Synthesis of Thromboxane A 2 by Platelets from a Patient with Hemolytic Uremic Syndrome
Author(s) -
Hidaka Toshihiro,
Ogura Ryohei,
Furuno Hiroaki,
Tanaka Chihei,
Yamashita Fumio
Publication year - 1986
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1986.tb00700.x
Subject(s) - medicine , platelet , thromboxane , arachidonic acid , thromboxane a2 , platelet factor 4 , thromboxane a synthase , immunology , endocrinology , biochemistry , chemistry , enzyme
Increased thromboxane synthesis capacity was demonstrated in platelets from a patient with hemolytic uremic syndrome by the measurement of [1‐ 14 C] TxB 2 converted from [1‐ 14 C] arachidonic acid. Whether such potentiated platelets are a possible risk factor of this disease is discussed.