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Hypereosinophilia Secondary to Varicella in a Hyperimmunoglobulinemia E Syndrome
Author(s) -
Matsumoto Tomoaki,
Miyamoto Yoshiyuki,
Miura Kazunori
Publication year - 1985
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1985.tb00643.x
Subject(s) - hypereosinophilia , medicine , eosinophilia , convalescence , chickenpox , hypereosinophilic syndrome , bone marrow , dermatology , peripheral blood , pathogenesis , immunology , pathology , virus
Abstract A seven‐year‐old boy with hyperimmunoglobulinemia E (HIE) syndrome showed hypereosinophilia up to 49,000 per cubic millimeter (cumm) in his convalescence from a severe and protracted attack of varicella. Hypereosinophilia persisted for 40 days. Eosinophils seen in the bone marrow as well as in the peripheral blood were morphologically normal and a majority of them in the marrow were maturated. Since eosinophilia after varicella is not common, it is suggested that the pathogenesis of eosinophilia observed in this case may be associated with impaired immunity of HIE syndrome. Further studies on a large number of cases are necessary to confirm this.