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The Screening of Patients with Extrahepatic Biliary Atresia by Measuring Total Bile Acids Absoredin Dried Blood Spots
Author(s) -
Matsui Akira,
Fujimoto Takako,
Takazawa Yoshie,
Kasano Yasuo,
Okaniwa Mariko,
Kamoshita Shigehiko
Publication year - 1985
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1985.tb00636.x
Subject(s) - medicine , biliary atresia , dried blood , gastroenterology , screening test , spots , population , chromatography , pathology , pediatrics , chemistry , transplantation , environmental health , liver transplantation
The efficency was assessed of the screening for extrahepatic biliary atresia by measuring total bile acids absorbed in dried blood spots at around 5 days of age. When the cut‐off level was 54.0 μmol/l, the sensitivity, the specificty and the efficiency of the screening test were 87.9%, 93.9% and 93.9% respectively. The case‐finding rate was 0.009% in this type of screening which was three times as many as an early case‐finding rate by population screening. These results suggest that teh efficiency of this screening is acceptable.