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Glomerular Basement Membrane Antigens in Various Renal Diseases in Childhood
Author(s) -
Miyata Hiroshi,
Yamamoto Takashi,
Murata Ryogo,
Makai Sunao
Publication year - 1984
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1984.tb01855.x
Subject(s) - medicine , antigen , glomerular basement membrane , nephrosis , membranoproliferative glomerulonephritis , radioimmunoassay , glomerulonephritis , urinary system , basement membrane , excretion , immunology , endocrinology , pathology , kidney
Urinary glomerular basement membrane (GBM) antigens were determined by radioimmunoassay in children with various glomerular diseases. The excretion of the GBM protein antigens was about one mg/g of urinary protein in most patients, except for patients with minimal change nephrosis. Although the GBM antigens were not uniform substances, the excretion of the GBM glycoprotein antigens was greatest in patients with membranoproliferative glomerulonephritis and rapidly progressive glomerulonephritis.