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Angiospermic Changes of Coronary Aneurysms in Kawasaki Disease
Author(s) -
Kawachi Kanji,
Kitamura Soichiro,
Oyama Choken,
Koh Shigeo,
Morita Ryuichi,
Yamada Yoshiki,
Kawashima Yasunaru
Publication year - 1983
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1983.tb01682.x
Subject(s) - medicine , kawasaki disease , cardiology , calcification , coronary arteries , coronary thrombosis , stenosis , thrombus , thrombosis , artery , right coronary artery , aneurysm , coronary artery aneurysm , surgery , radiology , coronary angiography , myocardial infarction
The fate of coronary aneurysms in Kawasaki disease or MCLS was examined by follow‐up studies on 9 patients with multiple bilateral aneurysms in the coronary arteries demonstrated by coronary arteriography. Their ages at the time if first examination ranged from 0.3 to 11 years (mean, 4.1 years). The mean interval between the onset of acute illness and the initial examination was 15.8 months, and the mean interval between the first and second examination was 17.9 months. Eight of the nine patients received anticoagulants between examinations. The second coronary arteriogram showed morphologic changes of the aneueysm from the time of the first examination: changes were seen in the right coronary artery area in 8 patients (89%) and in the left coronary artery area in 7 patients. These morphologuic changes seemed to be mainly secondary to thrombus formation, calcification, stenosis and/or obstruction of the aneuryms. Thus, coronary aneuryms in Kawasaki disease were transformed despite the use of anticoagulants. It is considered that multiple large coronary aneurysms will not healed or disappear, but are simply transformed as a result of their thrombosis and/or calcification.