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Anti‐infective Substances in Human Colostrum and Milk
Author(s) -
Uechi M.,
Ikezawa Y.,
Kosuge K.
Publication year - 1980
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1980.tb00514.x
Subject(s) - lactoferrin , colostrum , phagocytosis , staphylococcus aureus , medicine , in vitro , microbiology and biotechnology , antibody , immunology , biology , biochemistry , bacteria , genetics
We tried to measure accurately the lactoferrin concentration in human colostrum, and to study the morphology and function of human colostral cells. IgG and IgM concentrations were both very low, but IgA concentration was high in human colostrum. Lactoferrin concentration was 375‐284 mg/dl during postparturition period. We detected the IgG‐Fc and C3 receptor on the surface of colostral macrophage morphologically. Percentages of the E‐ and EA‐rosette forming cells of colostral lymphocytes were mean 18.5% and 5.9% during postparturition period respectively. We recognized that human colostral cells have phagocytosis and killing functions against staphylococcus aureus 209P in vitro.