Premium
Mumps Meningoencephalitis in Children
Author(s) -
Nakao Tooru,
Miura Ryoichi
Publication year - 1970
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.1970.tb02801.x
Subject(s) - medicine , pleocytosis , meningoencephalitis , parotitis , incidence (geometry) , vomiting , nausea , abdominal pain , pediatrics , cerebrospinal fluid , meningitis , gastroenterology , immunology , surgery , physics , optics
Summary A total of 238 patients with mumps meningoencephalitis was observed during the 13 years period, 1953–1966. Yearly and monthly incidence was variable and seemed to depend upon the extent of epidemic of parotitis. Highest incidence in age was from 3 to 8. Males were affected about twice more than females. Main symptoms were fever, nausea, vomiting, headache and abdominal pain. Meningoencephalitis followed the involvement of salivary glands in most cases. Cerebrospinal fluid findings did not essentially differ from those of meningitic cases caused by other kind of virus, but the grade and duration of pleocytosis were much higher and longer. Amylase levels in serum and urine were elevated in most cases, and pancreatic involvement was suspected in case of high levels of amylase and abdominal pain. A case of acute cerebellar ataxia was found to be associated with mumps virus infection serologically.