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Extrapulmonary involvement in patients with sarcoidosis in Turkey
Author(s) -
OKUMUS GULFER,
MUSELLIM BENAN,
CETINKAYA ERDOGAN,
TURKER HATICE,
UZASLAN ESRA,
YENTURK ESIN,
UZUN OGUZ,
SAGLAM LEYLA,
KUMBASAR OZLEM OZDEMIR,
CELIK GOKHAN,
ANNAKKAYA ALI NIHAT,
ALTIAY GUNDENIZ,
TABAK LEVENT,
SAKAR AYSIN,
KITER GOKSEL,
ERTURAN SERDAR,
TURKTAS HALUK,
YALNIZ ENVER,
AKKOCLU ATILLA,
OGUS CANDAN,
DOGAN OMER TAMER,
OZKAN METIN,
AKTOGU SERIR,
UZEL ISIL,
ONGEN GUL
Publication year - 2011
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/j.1440-1843.2010.01878.x
Subject(s) - medicine , sarcoidosis , concomitant , incidence (geometry) , dermatology , presentation (obstetrics) , lymph node , surgery , physics , optics
Background and objective: Extrapulmonary sarcoidosis is common, and is almost always associated with concomitant thoracic involvement. Extrapulmonary manifestations vary on the basis of gender, age at presentation and ethnicity. The aim of this study was to investigate extrapulmonary involvement in patients with sarcoidosis in Turkey. Methods: This study was conducted by Turkish Thoracic Society Clinical Problems Study Group. New cases of sarcoidosis between 1 June 2004 and 31 May 2006 were recorded on electronic case record forms sent to all potential investigators and information about extrapulmonary involvement was collected. Results: One hundred and nineteen of 293 patients (83 female, 36 male, mean age = 45 ± 12 years) had extrapulmonary involvement in this study (40.6%). The median time to diagnosis was 6 months and this was longer than patients with just thoracic sarcoidosis ( P = 0.001). Extrapulmonary symptoms were present in 181 (61.8%) patients, and skin lesions, arthralgia and back pain were the commonest (33.4%, 20.8% and 16.4%, respectively). Incidence of organ involvement was independent of age with the exception of ocular involvement, which was higher in those under the age of 40 years ( P = 0.007). Conclusions: Skin and peripheral lymph node involvement were the most common sites of extrapulmonary involvement and ocular involvement was more common in those under the age of 40 years in patients with sarcoidosis in a Turkish population.