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Does early pulmonary rehabilitation reduce acute health‐care utilization in COPD patients admitted with an exacerbation? A randomized controlled study
Author(s) -
EATON Tam,
YOUNG Pam,
FERGUSSON Wendy,
MOODIE Lisa,
ZENG Irene,
O'KANE Fiona,
GOOD Nichola,
RHODES Leanne,
POOLE Phillippa,
KOLBE John
Publication year - 2009
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/j.1440-1843.2008.01418.x
Subject(s) - medicine , copd , pulmonary rehabilitation , exacerbation , randomized controlled trial , rehabilitation , physical therapy , randomization , quality of life (healthcare) , prospective cohort study , pulmonary function testing , emergency medicine , nursing
Background and objective: In COPD, hospital admissions and readmissions account for the majority of health‐care costs. The aim of this prospective randomized controlled study was to determine if early pulmonary rehabilitation, commenced as an inpatient and continued after discharge, reduced acute health‐care utilization. Methods: Consecutive COPD patients ( n = 397), admitted with an exacerbation, were screened: 228 satisfied the eligibility criteria, of whom 97 consented to randomization to rehabilitation or usual care. Both intention‐to‐treat and per‐protocol analyses are reported with adherence being defined a priori as participation in at least 75% of rehabilitation sessions. Results: The participants were elderly with severe impairment of pulmonary function, poor health‐related quality of life and high COPD‐related morbidity. The rehabilitation group demonstrated a 23% (95% CI: 11–36%) risk of readmission at 3 months, with attendees having a 16% (95% CI: 0–32%) risk compared with 32% (95% CI: 19–45%) for usual care. These differences were not significant. There were a total of 79 COPD‐related readmission days (1.7 per patient, 95% CI: 0.6–2.7, P = 0.19) in the rehabilitation group, compared with 25 (1.3 per patient, 95% CI: 0–3.1, P = 0.17) for the attendees and 209 (4.2 per patient, 95% CI: 1.7–6.7) for usual care. The BMI, airflow obstruction, dyspnoea and exercise capacity index showed a non‐significant trend to greater improvement among attendees compared with those receiving usual care (5.5 (2.3) and 5.6 (2.7) at baseline, improving to 3.7 (1.9) and 4.5 (2.5), respectively, at 3 months). No adverse effects were identified. Conclusions: Early inpatient–outpatient rehabilitation for COPD patients admitted with an exacerbation was feasible and safe, and was associated with a non‐significant trend towards reduced acute health‐care utilization.