Premium
Solitary pleural plasmacytomas manifested as a massive pleural effusion without evidence of monoclonal gammopathy
Author(s) -
FENG Po Hao,
HUANG ChungChi,
WANG ChihWei,
WU YaoKuang,
TSAI YingHuang
Publication year - 2008
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/j.1440-1843.2008.01319.x
Subject(s) - medicine , paraproteins , plasmacytoma , pleural effusion , multiple myeloma , pathology , radiation therapy , monoclonal , radiology , monoclonal antibody , antibody , immunology
The majority of extramedullary plasmacytomas involve the upper respiratory tract but only a few are associated with serum monoclonal gammopathy. Most extramedullary plasmacytomas respond to local radiotherapy and have a better prognosis than multiple myeloma. Solitary plasmacytomas, involving the pleura, are very rare. This case report describes a patient with a solitary extramedullary plasmacytoma involving the pleura, and no evidence of serum, urine or pleural fluid paraproteins. Diagnosis was made by strongly positive immunohistochemical stains with CD38, CD138 and MUM‐1 of the pleural tumour. The response to both radiotherapy and chemotherapy was poor and the patient died shortly after diagnosis.