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Tracheo‐broncho‐bronchiolar lesions in Sjögren's syndrome
Author(s) -
KOBAYASHI Hideo,
KANOH Soichiro,
MOTOYOSHI Kazuo,
AIDA Shinsuke
Publication year - 2008
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/j.1440-1843.2007.01155.x
Subject(s) - medicine , sjögren syndrome , dermatology , pathology , systemic disease , disease
A 53‐year‐old woman reported having a persistent cough and bloody sputum. She did not smoke but had received a diagnosis of Sjögren's syndrome. Chest CT revealed middle lobe syndrome, bronchiectasis and diffuse centrilobular nodular lesions. Bronchoscopy displayed multiple whitish polypoid lesions protruding from the cartilage rings and tracheobronchopathia osteochondroplastica was histologically confirmed by the presence of bony tissue in the tracheo‐bronchial wall. Video‐assisted thoracoscopic biopsy demonstrated lymphocyte aggregation causing follicular broncho‐bronchiolitis. Erythromycin therapy resulted in improvement of the follicular bronchiolitis but not the tracheobronchopathia osteochondroplastica.