Premium
Primary Sjogren's syndrome complicated by bilateral pleural effusion
Author(s) -
TESHIGAWARA Katsunobu,
KAKIZAKI Satoru,
HORIYA Madoka,
KIKUCHI Yuki,
HASHIDA Tetsu,
TOMIZAWA Yoshio,
SOHARA Naondo,
SATO Ken,
TAKAGI Hitoshi,
MATSUZAKI Shinichi,
MORI Masatomo
Publication year - 2008
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/j.1440-1843.2007.01149.x
Subject(s) - medicine , xerophthalmia , malignancy , schirmer test , pleural effusion , sjögren syndrome , pathology , antibody , effusion , dermatology , gastroenterology , immunopathology , systemic disease , immunology , dry eyes , surgery , vitamin a deficiency , retinol , vitamin , ophthalmology
Sjogren's syndrome can cause many organic changes, but is rarely accompanied by pleuritis. We report a 65‐year‐old patient with primary Sjogren's syndrome who developed bilateral pleuritis with moderately large effusions. He was diagnosed as having Sjogren's syndrome, based on xerophthalmia, xerostomia, positive results for anti‐Sjogren's syndrome (anti‐SS‐A/SS‐B) antibodies, the Schirmer test and biopsy findings in the minor salivary glands. The pleural fluid was lymphocyte rich and contained high levels of anti‐SS‐A/SS‐B antibodies. There was no evidence of infection, malignancy or other collagen diseases which cause pleuritis. We conclude that this case adds to the eight previously published reports of primary Sjogren's syndrome complicated by pleural effusion.