Trastuzumab (Herceptin)‐associated lung injury | Zendy

VAHID Bobbak | Zendy; MEHROTRA Anita | Zendy

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Trastuzumab (Herceptin)‐associated lung injury

Author(s) -

VAHID Bobbak,

MEHROTRA Anita

Publication year - 2006

Publication title -

respirology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.857

H-Index - 85

eISSN - 1440-1843

pISSN - 1323-7799

DOI - 10.1111/j.1440-1843.2006.00907.x

Subject(s) - medicine , trastuzumab , pneumonitis , neutrophilia , hypersensitivity pneumonitis , bronchoalveolar lavage , lung cancer , lung , lymphocytosis , breast cancer , radiology , oncology , cancer

We report a case of trastuzumab pneumonitis in a patient with metastatic breast cancer. Bronchoalveolar lavage showed marked neutrophilia. A CT scan of the chest showed diffuse ground‐glass opacities. The patient was treated with corticosteroids with a partial response. Trastuzumab‐associated pneumonitis is not well described, and data in the literature is sparse. We describe the clinical and radiographical findings of trastuzumab‐associated pneumonitis.

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