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Prediction of the maximal voluntary ventilation in healthy adult Chinese subjects
Author(s) -
Kor Ai Ching,
Ong Kian Chung,
Earnest Arul,
Wang Yee Tang
Publication year - 2004
Publication title -
respirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 85
eISSN - 1440-1843
pISSN - 1323-7799
DOI - 10.1111/j.1440-1843.2003.00532.x
Subject(s) - medicine , spirometer , regression analysis , population , physical therapy , statistics , spirometry , mathematics , asthma , exhaled nitric oxide , environmental health
Objectives: The aim of the present study was to investigate the relationship between the FEV 1 and maximal voluntary ventilation (MVV) in healthy adult Chinese subjects, and to determine the validity of existing prediction equations of MVV for use in the Chinese population. Methodology: Ninety‐five healthy subjects (48 male and 47 female) stratified into five age groups (from 20 to 70 years) for both sexes were recruited from the general population. The FEV 1 and MVV of these subjects were measured with a clinical spirometer. The MVV was determined using the closed‐circuit technique. The MVV was assessed for 12 s and values were calculated to obtain L/min. Multiple regression analysis was used to develop equations to predict MVV with age, height, FEV 1 as well as with FEV 1 alone as predictor variables. One‐sample t ‐tests were used to compare the actual values of MVV for the subjects with their predicted values using equations from previous studies of MVV in healthy subjects. Results: Using FEV 1 only, the following predictive equation was obtained: MVV = FEV 1 × 45.12 − 15.85 (adjusted r 2 = 0.792). Predicted MVV values using previously cited equations, including MVV = FEV 1 × 35 or 40, were all significantly different from the actual MVV values of these subjects. Conclusions: The relationship between MVV and FEV 1 among healthy adult Chinese subjects is described. Previously cited equations describing the relationship between FEV 1 and MVV cannot be applied to healthy adult Chinese subjects.