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Peripheral T‐cell lymphoma arising from an intraglandular lymph node in the parotid gland: A case report and literature review
Author(s) -
Yanagawa Naoki,
Osakabe Mitsumasa,
Furuse Hidekazu,
Maeda Kunihiko,
Tamura Gen
Publication year - 2012
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.2011.02747.x
Subject(s) - pathology , cd30 , cd5 , parotid gland , medicine , lymphoma , lymph node , t cell lymphoma , cd15 , cd34 , biology , stem cell , genetics
T/NK‐cell lymphoma of the salivary gland is rare. A 58‐year‐old man complained of a tumor mass in the left parotid gland region and he was diagnosed to have a left parotid tumor. The tumor was subsequently resected, revealing a diffuse growth pattern of medium to large sized atypical cells. The tumor was surrounded by fibrous connective tissue in the form of a capsule, and those were positive for CD3, CD4, CD5 and CD30, but negative for Bcl2, CD8, CD10, CD15, CD20, CD25, CD56, CD79a, CD246, EMA, granzyme B, TdT and TIA‐1. There was no molecular evidence of Epstein‐Barr virus (EBV) infection. It was diagnosed as peripheral T‐cell lymphoma (PTCL) arising from an intraglandular lymph node in the parotid gland. In conclusion, Only 17 cases of primary T/NK‐cell lymphoma of the salivary glands have been recorded until now, and the characteristics of these are not clear yet. Additional study is needed.