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Primary cardiac synovial sarcoma: A case report and literature review
Author(s) -
Yokouchi Yuki,
Hiruta Nobuyuki,
Oharaseki Toshiaki,
Ihara Fumie,
Oda Yoshinao,
Ito Shingo,
Yamashita Hiromasa,
Ozaki Shigeyuki,
Gomi Tatsuya,
Takahashi Kei
Publication year - 2011
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.2010.02631.x
Subject(s) - medicine , synovial sarcoma , palpitations , sarcoma , pathology , pericardial effusion , surgery
Primary cardiac synovial sarcoma is a rare disease. A 51‐year‐old man visited our hospital with the chief complaint of palpitations and shortness of breath while exercising. Copious bloody pericardial effusion and a multicystic intrapericardial tumor were detected. A primary cardiac malignant tumor was suspected, an open‐chest tumor resection was performed with the objectives of diagnosis and treatment. Histologically, the tumor cells were uniformly spindle‐shaped with an ovoid or oval nucleus, they had proliferated in fascicular fashion. In addition myxoid degeneration, a hemangiopericytomatous vascular pattern and pseudorosette formation were seen in some areas of the tumor. Based on the histopathological and immunohistochemical findings and reverse transcription polymerase chain reaction detection of SS18‐SSX1 fusion transcripts, a monophasic fibrous type synovial sarcoma was diagnosed. Postoperative radiation therapy was administered and there had been no recurrence 9 months after the surgery.