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Dermatofibrosarcoma protuberans of the breast skin
Author(s) -
Kim Taeeun,
Choi YoonLa,
Park HaYoung,
Song JiYoung,
Shin Jung Hee,
Nam Seok Jin,
Ahn Geunghwan
Publication year - 2010
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.2010.02599.x
Subject(s) - dermatofibrosarcoma protuberans , cd34 , pathology , medicine , dermatofibrosarcoma , biopsy , lesion , soft tissue , sarcoma , population , wide local excision , biology , stem cell , genetics , environmental health
A case of a 26‐year‐old woman with dermatofibrosarcoma protuberans of the breast skin is described. She had noticed a palpable mass with redness 15 years previously, but it had begun to grow rapidly with swelling and redness two months before presenting. Ultrasonography and biopsy demonstrated a possibility of sarcoma of the breast. Wide excision was performed to confirm the diagnosis. Histologically, the tumor was composed of a uniform population of fibroblasts in a distinct storiform pattern. CD34 immunostaining showed diffuse reactivity. Platelet‐derived growth factor β break‐apart fluorescence in situ hybridization analysis showed a split‐signal pattern which supported the diagnosis of dermatofibrosarcoma protuberans in the skin of the breast. It is important to diagnose a soft tissue lesion accurately when it occurs in the breast.