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Unclassified epithelioid vascular tumor with hemangioendotheliomatous features and lymphatic differentiation
Author(s) -
Oshiro Yumi,
Kohashi Kenichi,
Oda Yoshinao,
Tsuneyoshi Masazumi,
Shono Yoshitaka
Publication year - 2009
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.2009.02386.x
Subject(s) - pathology , cd31 , cd34 , immunohistochemistry , lymphatic system , differential diagnosis , epithelioid hemangioendothelioma , biology , anatomy , medicine , stem cell , microbiology and biotechnology
Reported herein is an unusual vascular tumor that arose in the little finger of a 10‐year‐old boy. The tumor consisted of a vaguely demarcated nodular mass, which was located in the subcutaneous layer and measured 1 cm in diameter. Microscopic characteristic findings of this tumor were epithelioid nests, admixed with focal components with retiform features, intraluminal papillary tufts, and spindle cells. These features resemble those of subtypes of hemangioendotheliomas. On immunohistochemistry CD31, CD34 and D2‐40 were diffusely expressed in the tumor cells, representing prominent lymphatic differentiation. These findings are not characteristic of any established types of vascular tumors. The differential diagnosis for the current peculiar tumor are discussed.