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Primary invasive micropapillary carcinoma of the stomach
Author(s) -
Shimoda Masayuki,
Okada Yasunori,
Hayashi Yuichiro,
Hatano Satoshi,
Kawakubo Hirofumi,
Omori Tai,
Ishii Seiichiro,
Sugiura Hitoshi
Publication year - 2008
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.2008.02265.x
Subject(s) - stomach , pathology , medicine , curvatures of the stomach , lymph node , carcinoma , urinary bladder , histopathology , lymph , lung
Reported herein is the case of a 74‐year‐old man with an unusual gastric carcinoma that developed at the lesser curvature of the stomach. The tumor consisted of small clusters of carcinoma cells surrounded by clear spaces, with histopathology similar to invasive micropapillary carcinoma (IMPC) of the breast. The carcinoma cells, which had downregulation of E‐cadherin expression, invaded the subserous tissue and metastasized to the perigastric lymph nodes. IMPC, an unusual subtype of invasive breast carcinoma, is known to have frequent lymph node metastases, resulting in a poor clinical outcome. Although IMPC has been reported in breast, urinary bladder, ureter, lung, salivary gland and colon, to the best of the authors’ knowledge this is the first report of IMPC arising in the stomach. Presented here are the clinicopathological features of primary IMPC of the stomach.