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Hypereosinophilic syndrome associated with occlusive coronary thrombosis and right ventricular thrombus
Author(s) -
Sato Yuichiro,
Fukunaga Takashi,
Hayashi Tohru,
Asada Yujiro
Publication year - 2008
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.2007.02202.x
Subject(s) - medicine , thrombus , cardiology , thrombosis , autopsy , coronary thrombosis , ventricle , coronary arteries , hypereosinophilic syndrome , eosinophilia , right coronary artery , pathology , coronary angiography , artery , myocardial infarction
A 44‐year‐old man with HES who developed a large thrombus in the right ventricle as well as multiple occlusive coronary thrombi died of cardiac failure. Autopsy showed that a large thrombus in the right ventricle was associated with eosinophilic endocarditis. In addition, an occlusive thrombus formed in the circumflex and right coronary arteries with eosinophilic infiltrate in the walls. The findings suggest a causal relationship between coronary thrombosis and eosinophilia. To the authors' knowledge this is the first report to document the clinical and histological findings of coronary thrombosis in a patient with HES.