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Esophageal squamous cell carcinoma presenting with systemic arterial embolism
Author(s) -
Sentani Kazuhiro,
Nakanishi Yukihiro,
Ojima Hidenori,
Hamaguchi Tetsuya,
Shimoda Tadakazu
Publication year - 2007
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.2006.02067.x
Subject(s) - medicine , embolus , embolectomy , esophagus , arterial embolization , radiology , esophageal cancer , arterial embolism , superior vena cava syndrome , embolism , autopsy , cancer , superior vena cava , pathology , embolization , surgery , pulmonary embolism
Acute arterial occlusion as a result of embolization from a malignant tumor is rare and infrequently reported. Recently a 70‐year‐old man initially presented with acute arterial occlusion of the left lower limb. He underwent embolectomy, and embolus was diagnosed as a squamous cell carcinoma histologically. Subsequent upper gastrointestinal endoscopy showed superficial esophageal cancer in the thoracic esophagus. Although scheduled to undergo chemotherapy, he died of acute pneumonia on the 81st day from onset. Autopsy showed superficial esophageal cancer, measuring 1.5 cm in diameter, and widespread tumor extension into arterial vessels such as the left femoral artery, the superior mesenteric artery, bilateral intrapulmonary arteries and veins such as bilateral brachiocephalic vein to the supra vena cava, despite small tumor size and shallow tumor invasion depth of the submucosal layer. This case is particularly interesting because the cancer manifested as arterial cancer embolism.