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Oxyphilic cell variant of endometrioid adenocarcinoma
Author(s) -
Fukuoka Keiko,
Hirokawa Mitsuyoshi,
Shimizu Michio,
Fujiwara Keiichi,
Kohno Ichiro,
Shintaku Masayukl,
Manabe Toshiaki
Publication year - 1998
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1998.tb03978.x
Subject(s) - medicine , adenocarcinoma , clear cell , endometrium , uterus , pathology , cell , lymph node , clear cell adenocarcinoma , gynecology , immunohistochemistry , cancer , biology , genetics
A case of oxyphllk cell variant of endometrlold adenocarclnorna is presented. To the best of our knowledge, there have been only three such cases reported in the English literature. The patient was a 35‐yearold Japanese female (gravida 0, para 0). She was sllghtly obese with profuse vaginal bleeding. Histologlcal examlnation of the resected uterus revealed endometrlold adenocarcinoma with an exclusive oxyphllic cell component. There was no evidence of myornetrial Invasion nor lymph node metastases. Reported cases of oxyphilic cell varlant of endometrioid admocamlnoma, lncludlng the present case, were stages 0–1 and grades 1–2. Although further study is necessary to evaluate this variant, oxyphllk cell variant seems to be an early stage of ademcarcinoma and should be differentiated from eosinophllk mgtaplasia and other types of adenocarcinoma of the endometrium.