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A case report of renal cell tumor in a 45‐year‐old female mimicking lower portion nephrogenesis
Author(s) -
He Qun,
Ohaki Yoshiharu,
Mori Osamu,
Asano Goro,
Tuboi Narumi
Publication year - 1998
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1998.tb03926.x
Subject(s) - pathology , cytokeratin , biology , immunohistochemistry , stroma , cd34 , histology , cuboidal cell , adenocarcinoma , vimentin , clear cell , staining , ultrastructure , anatomy , cancer , medicine , microbiology and biotechnology , genetics , stem cell
This report describes a renal tumor with an unusual histology In a 45‐year‐old woman. The tumor was white in color, different from usual renal cell carcinoma, and mainly consisted of variously shaped tubules formed by flat or cuboid cells within marked edematous stroma. Elaborated branching or tubules arranged In a papillary pattern with focal spindle‐shaped cell proliferation were characteristic features. Immunohistochemical staining expressed diffusely positive for vlmentin and S‐100 protein, partially positive for cytokeratin and epithelial membrane antigen and negative for Leu‐M1, Leu‐7, CD34 and markers for muscle cells. Ultrastructural studies of the tumor cells showed adenocarcinoma‐IIke characteristics. According to these histological, Immunohistochemlcal and electron microscopy findings, it is suggested that this tumor be designated as unclassified renal cell carcinoma with histology mimicking lower‐nephron nephrogenesis.