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Non‐Hodgkin's lymphoma presenting with adrenal insufficiency and hypothyroidism: An autopsy case report
Author(s) -
Nasu Mlchlyo,
Aruga Moriyo,
Itami Jun,
Fujimoto Hajime,
Matsubara Osamu
Publication year - 1998
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1998.tb03883.x
Subject(s) - autopsy , medicine , pathology , lymphoma , adrenal insufficiency , general surgery
A 55‐year‐old male presented with an Initial manifestation of primary adrenal Insufficlency, hypothyroidism. Computed tomography scans showed enlarged bilateral adrenal glands and thyroid. A pathological diagnosis of diffuse large cell, B cell lymphoma was made by a needle biopsy of the adrenal gland. He was treated with combination chemotherapy and adrenal and thyroid hormone replacement. The lymphoma subsequently involved the central nervous system. He died of pneumonia 8 months after the presentation of the first symptom. The postmortem examination demonstrated a complete regression of lymphoma in the bilateral adrenal glands and thyroid. This Is an extremely rare case of coexistent lymphoma of the adrenal glands and the thyroid presenting with adrenal failure and hypothyroidism.