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Interdigitating reticulum cell tumor of Iymph node: A case report and Iiterature review
Author(s) -
Liu ShianMin,
Huang PingHung,
Liu Jacqueline Ming
Publication year - 1998
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1998.tb03869.x
Subject(s) - pathology , reticulum , lymph node , pathological , medicine , lymphoma , endoplasmic reticulum , biology , biochemistry
Interdigitating reticulum cell (IRC) tumor is a rare tumor arising from the antigen‐preaenting cell ‐ Interdigitating reticulum cell. A 41‐year‐old male presented with lumps in the left neck and bone pain. Further Investigations revealed multiple left neck and para‐aottic lymphadenopathy, and multiple bony lesions. Histological examination of the lymph node showed proliferation of unusual, large, round neoplastic cells mimicking large cell lymphoma. Immuno‐phenotypic and ultrastructural studies confirmed this tumor to be arising from an Interdigitating reticulum cell. A review of reported IRC tumors illustrates the variability of this tumor in clinical and pathological features, which differ from other dendritic reticulum cell tumors.