Premium
The clear cell variant of epithelioid intravenous leiomyomatosis of the uterus: Report of a case
Author(s) -
Han Hye Sung,
Park In Ae,
Kim Sung Hyup,
Lee Hyo Pyo
Publication year - 1998
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1111/j.1440-1827.1998.tb03857.x
Subject(s) - hysterectomy , pathology , cytoplasm , perivascular epithelioid cell , uterus , medicine , epithelioid cell , clear cell , smooth muscle , immunohistochemistry , biology , biochemistry
A case of very rare uterine clear cell epithelioid leiomyomatosls Is reported. The patient presented with a recurrent pelvlc mass after hysterectomy 2 years earlier. The recurrent tumor was located mainly In the vessels of the broad llgament as worm‐like plugs. The revlewed hysterectomy speclinen showed a typical multi‐lobuiated intramural mass together with worm‐like plugs wlthin the myometrlal vessels. Computer tomography exhlbited metastatic nodules In both lungs. According to an histologlcal examlnatlon, all the tumor cells were of epltheliold type and contalned abundant clear cytoplasm. Characteristic large, thick‐walled blood vessels were observed. Immunohisto‐chemical staining and ultrastructural examinatlon sup ported smooth‐muscle origin In this case. Electron mlcrosmplc study revealed that the clear cytoplasm was attributed to the presence of numerous dllated mitochondria that had lost their crlstae. The patient is still alive wlth the disease 28 months after surgery.